| 中文名称Chinese name
|
HIV CH505口腔途径感染婴儿猕猴模型 |
| 编号Model number |
|
| 英文名称English name |
HIV SHIV.C.CH505 orally infected of infant rhesus macaques model |
| 物种Species name |
猴
|
| 品系Strain name |
|
| 人类疾病Human diseases |
HIV |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
HIV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Six infant rhesus macaques were infected orally starting at 4 weeks of age with a repeated exposure regimen that has been successfully developed with SIVmac251 to simulate exposure to HIV by breastfeeding. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于HIV致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
杜克大学医学院@@https://www.dukehealth.org/locations/duke-university-medical-center |
| 参考文献Reference |
Simian-Human Immunodeficiency Virus SHIV.CH505-Infected Infant and Adult Rhesus Macaques Exhibit Similar Env-Specific Antibody Kinetics, despite Distinct T-Follicular Helper and Germinal Center B Cell Landscapes.,PMID:31092583,DOI:10.1128/JVI.00168-19 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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