HIV HIV-1 BLT 小鼠静脉感染模型

中文名称Chinese name	HIV HIV-1 BLT 小鼠静脉感染模型
编号Model number
英文名称English name	HIV HIV-1 BLT mice intravenously infected model
物种Species name	小鼠
品系Strain name
人类疾病Human diseases	HIV
传染性Infectivity	是
微生物Microorganism
类别Category	HIV感染动物模型
造模因素Modeling factors
制作方法Making method	HIV was diluted in PBS and mice were infected with a 2,500 TCID50 via tail vein infection. Infection with the H37Rv (tdTomato) strain of Mtb59 was performed using 250 CFU diluted in 40 ul of Dulbecco’s Phosphate-Buffered Saline (PBS, Cellgro, Manassas, VA, USA) via an intranasal route (20 ul/nare)
生物学特征Biological characteristics
医学用途Medical use	用于HIV致病机制研究、疫苗和药物评估。
临床表现Clinical manifestation
病理表现Pathology
发病天数Days of onset
发病过程Pathogenesis process
临床诊断Clinical diagnosis
评价模型成功的指标Indicators for evaluating model success
保藏单位Preservation unit	德克萨斯大学医学分校@@https://www.utsystem.edu/institutions/university-of-texas-medical-branch-at-galveston
参考文献Reference	Pulmonary Tuberculosis in Humanized Mice Infected with HIV-1,PMID:26908312,DOI:10.1038/srep21522
录入/更新时间Date	2021.7.20
备注Remarks