| 中文名称Chinese name
|
SARS-CoV Tor2 滴鼻感染129S6/SvEv 小鼠模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV Tor2 intranasally infected 129S6/SvEv mice model |
| 物种Species name |
小鼠
|
| 品系Strain name |
|
| 人类疾病Human diseases |
SARS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
SARS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Mice were subcutaneously with WKV vaccine plus alum, consisting of 50 mg inactivated virus plus 500 mg Alhydrogel in 0.2 ml 0.1 M PBS; Following vaccination at 0 and 4 weeks, group 2 mice were challenged at 7 weeks with the SARSCoV Tor2 strain. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于SARS-CoV致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
BC Centre for Disease Control@@http://covid-19.bccdc.ca |
| 参考文献Reference |
Evaluation of the safety, immunogenicity and pharmacokinetics of equine anti-SARS-CoV F(ab')(2) in macaque.,PMID:17996696,DOI:10.1016/j.intimp.2007.09.011 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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