2026年02月02日 星期一

> A/Anhui/1/2013(H7N9)气溶胶途径感染雪貂模型

实验动物名称laboratory animal A/Anhui/1/2013(H7N9)气溶胶途径感染雪貂模型
中文名称Chinese name A/Anhui/1/2013(H7N9)气溶胶途径感染雪貂模型
编号Number CMBP-PH-000029
性别Gender
年龄Age
体重Weight

传播组雪貂在合笼后第11天开始出现较明显的体重下降。

体温Weight

感染组雪貂在H7N9病毒接种的第1~2天使体温升高,体温升高0.5~2℃,体温升高持续3天左右。

总血量Total blood volume
全血比重Whole blood specific gravity
血压Blood pressure
舒张压Diastolic pressure
心搏Heart beat
血液渗透压Blood osmotic pressure
血细胞数Blood cell count
红细胞数Number of red blood cells
血红蛋白Hemoglobin
红细胞压积Red cell pressure product
红细胞平均直径Mean diameter of red blood cells
红细胞平均血红蛋白Red blood cell hemoglobin (H)
红细胞平均体积Red cell mean volume (V)
红细胞平胞血红蛋白浓度Red cell hemoglobin concentration (HC)
网织红细胞数Number of red blood cells
红细胞平均渗透性脆性试验Erythrocyte osmotic fragility test
白细胞数White blood cell count
中性粒细胞Neutrophils
嗜酸粒细胞Eosinophilic granulocyte
淋巴细胞Lymphocyte
单核细胞Monocyte
嗜酸粒细胞直接计数Direct count of eosinophils
血小板数Platelet count
出血时间Bleeding time
凝血时间Coagulation time
凝血酶原时间Prothrombin time
血块收缩时间Clot retraction time
部分凝血活酶时间Partial thromboplastin time
凝血酶时间Thrombin time
复钙时间Calcium complex time
凝血活酶生成试验Thromboplastin generation test
简易凝血活酶生成试验STGT
全血凝块溶解试验Whole blood clot lysis test
优球蛋白溶解时间Time of dissolution
纤维蛋白溶酶活性Fibrinolytic enzyme activity
纤维蛋白溶酶原Plasminogen
血浆鱼精蛋白副凝试验Plasma protamine paracoagulation test (3P)
乙醇凝试验Ethanol coagulation test
每搏排血量Cardiac output (SV)
心排血量Cardiac output (CO)
心脏指数Cardiac index (CI)
喷血(射血)分数Ejection (ejection fraction) (EF)
左心室舒张末压Left ventricular end diastolic pressure (LVEDP)
肺毛细血管总阻力Total pulmonary capillary resistance (PWP)
周围血管总阻力Total peripheral vascular resistance (TPR)
周围血管阻力Peripheral vascular resistance
肺小动脉阻力Total lung resistance
每搏作功指数Stroke work index
臂至舌循环时间Cycle time of arm to tongue
臂至肺循环时间Arm to pulmonary circulation time
肺至舌循环时间Lung to tongue circulation time
右房平均压Right atrial mean pressure
右室收缩压Right ventricular systolic pressure
上腔静脉压力Superior vena cava pressure
中心静脉压Central venous pressure
肺活量vital capacity
残气量Residual volume
肺总量Total lung volume
残气/肺总量Residual / total lung
无效腔量Void volume
参考文献Reference 1.Lili Xu, Linlin Bao, Wei Deng, et al. Novel Avian-Origin Human Influenza A(H7N9) Can Be Transmitted Between Ferrets via Respiratory Droplets[J]. Journal of Infectious Diseases, 2014, 209(4):551-556. 2.Bao L , Bi Y , Wong G , et al. Diverse biological characteristics and varied virulence of H7N9 from Wave 5[J]. Emerging Microbes & Infections, 2019, 8(1):94-102. 3.Shuran Gong, Feifei Qi, Fengdi Li, Qi Lv, Guanpeng Wang, Shunyi Wang, Jing Jiang, Lin Wang, Linlin Bao, Chuan Qin. Human-Derived A/Guangdong/Th005/2017 (H7N9) Exhibits Extremely High Replication in the Lungs of Ferrets and Is Highly Pathogenic in Chickens. Viruses 2019. 4. 邓巍,许黎黎,鲍琳琳,朱华,陈霆,李枫棣,吕琦,袁静,向志光,高凯,徐艳峰,黄澜,李彦红,姚艳丰,于品,雍卫东,张连峰,秦川.H7N9禽流感病毒对雪貂的致病性及传播力研究[J].中国实验动物学报, 2014,22(1):32-37.
录入/更新时间Date 2021.11.29
备注Remarks
心率heart rate
呼吸频率Respiratory rate
染色体数Chromosome number
代谢量Metabolic quantity
基础代谢率Basal metabolic rate
血液PHblood PH
肺总阻力Total lung resistance
嗜碱粒细胞Eosinophilic granulocyte
右室舒张压Right ventricular diastolic pressure
疾病名称Disease name H7N9禽流感
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