| 中文名称Chinese name
|
SARS-CoV MA15滴鼻感染 BALB/c小鼠模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV MA15 intranasally infection of BALB/c mouse model |
| 物种Species name |
小鼠
|
| 品系Strain name |
BALB/c小鼠
|
| 人类疾病Human diseases |
SARS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
SARS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Sham treatment (normal saline alone), RTD-1 alone (5 mg/kg, two doses), SARS-CoV (3 " 10^5 PFU MA15) with RTD-1 treatment, and SARS-CoV alone. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于SARS-CoV致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
美国爱荷华大学@@https://uiowa.edu/ |
| 参考文献Reference |
Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease.,PMID:19710146,DOI:10.1128/JVI.01363-09 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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