HIV SIVmac251 静脉途径感染猕猴模型

中文名称Chinese name	HIV SIVmac251 静脉途径感染猕猴模型
编号Model number
英文名称English name	HIV SIVmac251 intravenously infected of rhesus macaques model
物种Species name	猴
品系Strain name
人类疾病Human diseases	HIV
传染性Infectivity	是
微生物Microorganism
类别Category	HIV感染动物模型
造模因素Modeling factors
制作方法Making method	All animals were infected intravenously at the same time with ~100 animal infectious doses of SIVmac251 that was obtained from Dr. Norman Letvin at Harvard Medical School.
生物学特征Biological characteristics
医学用途Medical use	用于HIV致病机制研究、疫苗和药物评估。
临床表现Clinical manifestation
病理表现Pathology
发病天数Days of onset
发病过程Pathogenesis process
临床诊断Clinical diagnosis
评价模型成功的指标Indicators for evaluating model success
保藏单位Preservation unit	美国健康科学大学@@https://www.usuhs.edu/
参考文献Reference	Gender differences in innate responses and gene expression profiles in memory CD4 T cells are apparent very early during acute simian immunodeficiency virus infection.,PMID:31490965,DOI:10.1371/journal.pone.0221159
录入/更新时间Date	2021.7.20
备注Remarks