| 中文名称Chinese name
|
SARS-CoV-2 鼻内感染树鼩模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV-2 nasally infected tree shrew model |
| 物种Species name |
树鼩
|
| 品系Strain name |
树鼩
|
| 人类疾病Human diseases |
COVID-19 |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
新型冠状病毒动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
After baseline data and samples were collected right before virus inoculation, each of tree shrew was inoculated with 1 ml 10**6 pfu SARS-CoV-2 nasally (500ul/each nostril). |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于新冠肺炎COVID-19致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
国家昆明高等级生物安全灵长类动物实验中心@@https://www.pumch.cn/videos.html@@北京协和医学院@@http://www.cams.ac.cn/ |
| 参考文献Reference |
Susceptibility of tree shrew to SARS-CoV-2 infection,NA,DOI:10.1101/2020.04.30.029736 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|