| 中文名称Chinese name
|
HIV-2 HIV-2 287静脉途径感染猪尾猕猴模型 |
| 编号Model number |
|
| 英文名称English name |
HIV-2 HIV-2 287 intravenously infected pig-tailed macaques model |
| 物种Species name |
猴
|
| 品系Strain name |
|
| 人类疾病Human diseases |
HIV |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
HIV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Twenty-seven pig-tailed macaques (M. nemestrina; ages 1.2–3.1 years, median, 2.1 years; 11 male, 16 female) were inoculated intravenously with 50 TCID50 (50% tissue culture infectious doses) of HIV-2287. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于HIV致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
病毒在血液中复制 |
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
华盛顿大学@@https://www.washington.edu/ |
| 参考文献Reference |
Rapid shift from virally infected cells to germinal center-retained virus after HIV-2 infection of macaques.,PMID:10751345,DOI:10.1016/S0002-9440(10)64990-5 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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