| 中文名称Chinese name
|
SARS-CoV rSARS-CoV ΔORF7ab 滴鼻感染叙利亚仓鼠模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV rSARS-CoV ΔORF7ab intranasally infected golden Syrian hamster model |
| 物种Species name |
仓鼠
|
| 品系Strain name |
叙利亚仓鼠
|
| 人类疾病Human diseases |
SARS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
SARS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
virus injection: 50ul per nare, CP administration via i.p. route, subsequent dose began on 2d post infection and continued every 4 days until 42dpi |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于SARS-CoV致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
华盛顿大学医学院分子微生物学系@@https://microbiology.wustl.edu/ |
| 参考文献Reference |
An immunosuppressed Syrian golden hamster model for SARS-CoV infection.,PMID:18760437,DOI:10.1016/j.virol.2008.07.026 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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