| 中文名称Chinese name
|
SARS-CoV-2 BetaCoV/Wuhan/IVDC-HB-01/2019 滴鼻感染猫模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV-2 BetaCoV/Wuhan/IVDC-HB-01/2019 intransally infection cat model |
| 物种Species name |
|
| 品系Strain name |
|
| 人类疾病Human diseases |
COVID-19 |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
新型冠状病毒动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Male/female mixed ten outbred domestic juvenile cats (aged 70–100 days) and ten outbred subadult cats (aged 6–9 months), obtained from the National Engineering Research Center of Veterinary Biologics CORP. (Harbin, China) were used in this study. To evaluate the replication of SARS-CoV-2, four juvenile cats and four subadult cats were intranasally inoculated with 10**5 PFU of CTan-H. Two cats of each age group were euthanized on day 3 p.i. and day 6 p.i., respectively |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于新冠肺炎COVID-19致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
中国农业科学院哈尔滨兽医研究所@@http://www.hvri.ac.cn |
| 参考文献Reference |
Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2,PMID:32269068,DOI:10.1126/science.abb7015 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
当前位置：
