| 中文名称Chinese name
|
SARS-CoV-2 IVCAS 6.7512 气管内感染猕猴模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV-2 IVCAS 6.7512 intratracheal infection rhesus macaque model |
| 物种Species name |
猴
|
| 品系Strain name |
|
| 人类疾病Human diseases |
COVID-19 |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
新型冠状病毒动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Six rhesus macaques (three males, three females; age 6–12 years, weight 5–12 kg), were inoculated with SARS-CoV–2 (7*10**6｜TCID50) diluted in DMEM. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于新冠肺炎COVID-19致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
体重下降 |
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
中国科学院武汉病毒研究所@@http://www.whiov.cas.cn/ |
| 参考文献Reference |
A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV)infected pneumonia(standard version),PMID:32029004,DOI:10.1186/s40779-020-0233-6 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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