| 中文名称Chinese name
|
SARS-CoV-2 2019-nCoV/USA-WA1/2020 滴鼻感染转基因 Ces1c-/-小鼠模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV-2 2019-nCoV/USA-WA1/2020 intransally infection transgenic Ces1c-/- mouse model |
| 物种Species name |
小鼠
|
| 品系Strain name |
|
| 人类疾病Human diseases |
COVID-19 |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
新型冠状病毒动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
|
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于新冠肺炎COVID-19致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
病毒在肺中复制 |
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
范德堡大學醫學中心@@https://search.vanderbilthealth.com/locations/vanderbilt-university-medical-center?utm_source=Yext&utm_medium=Listings&utm_campaign=WebsiteClicks_Facility&utm_content=338 |
| 参考文献Reference |
Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice,PMID:32511392,DOI:10.1101/2020.04.27.064279 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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