| 中文名称Chinese name
|
MERS-CoV Al-Hasa_KFU-HKU13/2013口鼻途径感染羊驼模型 |
| 编号Model number |
|
| 英文名称English name |
MERS-CoV Al-Hasa_KFU-HKU13/2013 oronasally infection alpaca model |
| 物种Species name |
羊驼
|
| 品系Strain name |
|
| 人类疾病Human diseases |
MERS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
MERS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
The 3 alpacas were exposed oronasally to a 106 50% tissue culture infective dose of MERS-CoV in 5 mL of phosphate-buffered saline. The animals were monitored for 21 days, reexposed to a replicate challenge of MERS-CoV |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于MERS致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
澳大利亚动物健康实验室@@https://www.csiro.au/en/Research/Facilities/ACDP |
| 参考文献Reference |
Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus.,PMID:27070733,DOI:10.3201/eid2206.160007 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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