| 中文名称Chinese name
|
Hepatitis HDV腹腔途径感染hNTCP-Tg scid小鼠模型 |
| 编号Model number |
|
| 英文名称English name |
Hepatitis HDV intraperitoneal infection hNTCP-Tg scid mouse model |
| 物种Species name |
小鼠
|
| 品系Strain name |
|
| 人类疾病Human diseases |
Hepatitis |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
肝炎感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
hNTCP-Tg homozygotes with homozygous Prkdc mutation (SCID) were i.p. inoculated with 5.3×1010 GEq of HDV 9 days after birth |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于肝炎致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
中国医学科学院&北京协和医学院http://english.cams.cn/graduate/160.html |
| 参考文献Reference |
Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection.,PMID:25795587,DOI:10.1038/nmicrobiol.2016.280 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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