| 中文名称Chinese name
|
SARS-CoV-2 BetaCoV/Munich/BavPat1/2020 气管滴鼻联合感染食蟹猴模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV-2 BetaCoV/Munich/BavPat1/2020 intranasally and intratracheally infected cynomolgus macaques model |
| 物种Species name |
|
| 品系Strain name |
食蟹猴
|
| 人类疾病Human diseases |
COVID-19 |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
新型冠状病毒动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
inoculated by a combined intratracheal (IT) and intranasal (IN) route with a SARS-CoV-2 strain from a German traveler returning from China, intranasal 0.25ml per nostril, intratracheal 4.5 ml |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于新冠肺炎COVID-19致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
鹿特丹伊拉斯姆斯大学医学中心@@https://www.erasmusmc.nl/en/research/departments/viroscience |
| 参考文献Reference |
Comparative pathogenesis of COVID-19, MERS,
and SARS in a nonhuman primate model,NA,DOI:10.1016/j.tranon.2019.05.006 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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