| 中文名称Chinese name
|
MERS-CoV HCoV-EMC/2012 直接接触感染羊驼模型 |
| 编号Model number |
|
| 英文名称English name |
MERS-CoV HCoV-EMC/2012 contact infected alpaca model |
| 物种Species name |
羊驼
|
| 品系Strain name |
|
| 人类疾病Human diseases |
MERS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
MERS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Two days later, alpacas A4–A6 were introduced into the same room as alpacas A1–A3 and housed together for the duration of the study.Animals A1–A6 were held in the facility for 70 days postinfection, and all 6 animals were then reinfected intranasally with 10^7 PFU of MERS-CoV. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于MERS致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
体温体重无明显变化，无鼻腔分泌物 |
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
美国科罗拉多州立大学@@https://www.colostate.edu |
| 参考文献Reference |
Infection, Replication, and Transmission of Middle East Respiratory Syndrome Coronavirus in Alpacas.,PMID:27070385,DOI:10.3201/2206.160192 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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