| 中文名称Chinese name
|
SARS-CoV-2 HB-01 气管内感染猕猴模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV-2 HB-01 intratracheally infection rhesus macaque model |
| 物种Species name |
猴
|
| 品系Strain name |
|
| 人类疾病Human diseases |
COVID-19 |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
新型冠状病毒动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
To develop a macaque animal infection model with SARS-CoV-2, three rhesus macaques (Macaca mulatta) (3-5 years old) and two 15 years old rhesus macaques were subsequently inoculated with SARS-CoV-2 by intratracheal routes containing 106 TCID50/mL. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于新冠肺炎COVID-19致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
体重下降 |
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
北京协和医学院@@https://www.pumch.cn/videos.html |
| 参考文献Reference |
Age-related rhesus macaque models of CovID-19,PMID:32318665,DOI:10.1002/ame2.12108 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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