| 中文名称Chinese name
|
SARS-CoV-2 IVDC-HB-01 滴鼻感染hACE2小鼠模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV-2 IVDC-HB-01 Infected hACE2 Transgenic Mice model |
| 物种Species name |
小鼠
|
| 品系Strain name |
|
| 人类疾病Human diseases |
COVID-19 |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
新型冠状病毒动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
The prophylactic efficacy was examined by intraperitoneally injecting 20 mg/kg (of mice body weight) BD-368-2 into hACE2 transgenic mice 24 h before viral infection. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于新冠肺炎COVID-19致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
北京大学未来基因诊断高精尖创新中心@@https://icg.pku.edu.cn/ |
| 参考文献Reference |
Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells,PMID:32425270,DOI:10.1016/j.cell.2020.05.025 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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