| 备注Remarks |
[1] Rowshanravan B, Halliday N, Sansom DM. CTLA-4: a moving target in immunotherapy[J]. Blood, 2018, 131(1): 58-67.
[2] Park J, Kwon M, Shin EC. Immune checkpoint inhibitors for cancer treatment[J]. Archives of pharmacal research, 2016, 39(11): 1577-87.
[3] Lute KD, May KF, Jr., Lu P, et al. Human CTLA4 knock-in mice unravel the quantitative link between tumor immunity and autoimmunity induced by anti-CTLA-4 antibodies[J]. Blood, 2005, 106(9): 3127-33.
[4] Ipilimumab[J]. Drugs in R&D, 2010, 10(2): 97-110.
[5] Rotte A. Combination of CTLA-4 and PD-1 blockers for treatment of cancer[J]. Journal of experimental & clinical cancer research : CR, 2019, 38(1): 255.
[6] Tremelimumab[J]. Drugs in R&D, 2010, 10(2): 123-32.
[7] Antonia S, Goldberg SB, Balmanoukian A, et al. Safety and antitumour activity of durvalumab plus tremelimumab in non-small cell lung cancer: a multicentre, phase 1b study[J]. The Lancet Oncology, 2016, 17(3): 299-308.
[8] Bahig H, Aubin F, Stagg J, et al. Phase I/II trial of Durvalumab plus Tremelimumab and stereotactic body radiotherapy for metastatic head and neck carcinoma[J]. BMC cancer, 2019, 19(1): 68.
[9] Fumet JD, Isambert N, Hervieu A, et al. Phase Ib/II trial evaluating the safety, tolerability and immunological activity of durvalumab (MEDI4736) (anti-PD-L1) plus tremelimumab (anti-CTLA-4) combined with FOLFOX in patients with metastatic colorectal cancer[J]. ESMO open, 2018, 3(4): e000375.
[10] Lee JY, Kim JW, Lim MC, et al. A phase II study of neoadjuvant chemotherapy plus durvalumab and tremelimumab in advanced-stage ovarian cancer: a Korean Gynecologic Oncology Group Study (KGOG 3046), TRU-D[J]. Journal of gynecologic oncology, 2019, 30(6): e112.
[11] He M, Chai Y, Qi J, et al. Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies[J]. Oncotarget, 2017, 8(40): 67129-39.
|