| 品系名称Strain name
|
B6;129S4-Tubg2<tm1Sts>/StsRbrc小鼠 |
| 编号Number |
|
| 品系编号Strain number
|
|
| 物种 |
小鼠
|
| 英文名English name |
B6;129S4-Tubg2<tm1Sts>/StsRbrc mice |
| 别名Alias name |
TUBG2 knockout mouse |
| 类别Category |
congenic, mutant strain, targeted mutation |
| 基因信息Gene information |
微管蛋白，γ2，新霉素抗性基因 |
| 描述Description |
|
| 传代Generation |
|
| 外观特征Appearance features |
|
| 遗传特征Genetic characteristics |
congenic, mutant strain, targeted mutation |
| 培育历程Cultivation |
Developed by Drs. Akiko Yuba-Kubo and Shioichiro Tsukita at Kyoto University in 2001. A Pgk-neo cassette was inserted to replace exon 5 og Tobg2 gene. The mutant mice were backcrossed to C57BL/6 over 6 generation. |
| 相关亚系Related substrain |
|
| 图片Picture |
|
| 生物学特征Biological characteristics |
γ-微管蛋白在微管的成核中起着核心作用。Tubg2 是一种 γ-微管蛋白同种型，主要在大脑中检测到。Tubg2 纯合缺陷小鼠可存活，但有时会因运动功能受损而随着年龄增长而变得不育。 |
| 寿命与疾病Life-span and disease |
|
| 应用领域Application area |
发育生物学研究 神经生物学研究 |
| 饲养与繁殖Breeding and reproduction |
杂合子 x C57BL/6JJcl |
| 保种单位Preserving unit |
|
| 数据来源Data sources
|
MGI:3764481 |
| 录入/更新时间Date |
2021.9.15 |
| 备注Remarks |
|
| 品系可用性Strain Availability |
Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
| 特定条款和条件Specific Term and Conditions |
生物资源的接收者应事先获得提供者的书面同意。 |
| 保存状态Strain State Legend |
冷冻胚胎、冷冻精子 |
当前位置：
