| 中文名称Chinese name
|
SARS-CoV Urbani滴鼻感染叙利亚仓鼠模型 |
| 编号Model number |
|
| 英文名称English name |
SARS-CoV Urbani intranaslly infection Golden Syrian hamsters |
| 物种Species name |
仓鼠
|
| 品系Strain name |
叙利亚仓鼠
|
| 人类疾病Human diseases |
SARS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
SARS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
48 female Golden Syrian hamsters, 42 anesthetized hamsters received 100μl (10^3 TCID50) of SARS CoV (Urbani strain) intranasally, and as a control, six hamsters received 100μl of Leibovitz 15 (L15) medium (Invitrogen, Carlsbad, Calif.) intranasally. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于SARS-CoV致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
肺泡性浸润 |
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
美国疾病控制与预防中心@@https://www.cdc.gov/ |
| 参考文献Reference |
Severe acute respiratory syndrome coronavirus infection of golden Syrian hamsters.,PMID:15596843,DOI:10.1128/JVI.79.1.503-511.2005 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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