| 中文名称Chinese name
|
MERS-CoV Jordan-n3/2012 气管内感染猕猴模型 |
| 编号Model number |
|
| 英文名称English name |
MERS-CoV Jordan-n3/2012 intratracheal infected rhesus models |
| 物种Species name |
猴
|
| 品系Strain name |
|
| 人类疾病Human diseases |
MERS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
MERS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Group 2 received 5 *10^6PFU of MERS-JOR.. Inocula was performed with 2.5 mls of EMEM by placement of an endotracheal tube 4-5 cm above the carina followed by 2.5 ml s of PBS and air flush to ensure delivery of the inoculum. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于MERS致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
National Institute of Allergy and Infectious Diseases @@https://www.nih.gov/about-nih/what-we-do/nih-almanac/national-institute-allergy-infectious-diseases-niaid |
| 参考文献Reference |
3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012.,PMID:26828465,DOI:10.1016/j.virol.2016.01.004 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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