| 中文名称Chinese name
|
MERS-CoV EMC/2012滴鼻感染BALB/c小鼠模型 |
| 编号Model number |
|
| 英文名称English name |
MERS-CoV EMC/2012 intranasasally infection BALB/c mouse model |
| 物种Species name |
小鼠
|
| 品系Strain name |
BALB/c小鼠
|
| 人类疾病Human diseases |
MERS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
MERS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Ad5-hDPP4 transduced BALB/c mice (6wks, female) were injected intraperitoneally with 200 µL horse serum. 1 day after intranasal infection with 1×105 PFU MERS-CoV. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于MERS致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
中国人民解放军军事科学院军事医学研究院@@https://www.natureindex.com/institution-outputs/china/academy-of-military-medical-sciences-amms/51d26921140ba0bc70000000 |
| 参考文献Reference |
Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse model.,PMID:27890674,DOI:10.1016/j.antiviral.2016.11.016 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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