| 中文名称Chinese name
|
MERS-CoV Qatar15/2015 鼻内感染羊驼模型 |
| 编号Model number |
|
| 英文名称English name |
MERS-CoV Qatar15/2015 intranasally infected llamas model |
| 物种Species name |
羊驼
|
| 品系Strain name |
|
| 人类疾病Human diseases |
MERS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
MERS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Llamas were intranasally inoculated with 10^7 TCID50 dose of MERS-CoV Qatar15/2015 strain (GenBank Accesion MK280984) in 3 ml saline solution (1.5 ml in each nostril) using a nebulization device (LMA® MADgic®, Teleflex Inc.). |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于MERS致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
IRTA CReSA动物健康研究中心@@http://www.cresa.cat/cresa3/default.asp?mod=strmenu01&idioma=en |
| 参考文献Reference |
Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein.,PMID:31711379,DOI:10.1038/nmicrobiol.2016.291 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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