| 中文名称Chinese name
|
MERS-CoV HCoV EMC/2012滴鼻感染约克郡猪模型 |
| 编号Model number |
|
| 英文名称English name |
MERS-CoV HCoV EMC/2012 intransally infection Yorkshire pig model |
| 物种Species name |
猪
|
| 品系Strain name |
|
| 人类疾病Human diseases |
MERS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
MERS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
G1, MERS-CoV-inoculated pigs (P1–P5).G1 was inoculated with 107 TCID50 (50% tissue culture infectious dose) MERS-CoV (passage 7 human isolate HCoV EMC/2012) in 3 mL saline solution via intranasal route (1.5 mL in each nostril). |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于MERS致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
|
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
CReSA动物研究中心@@https://www.irta.cat/ca/centre/irta-cresa/ |
| 参考文献Reference |
Middle East respiratory syndrome coronavirus experimental transmission using a pig model.,PMID:28653496,DOI:10.1038/nmicrobiol.2016.294 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|