MERS-CoV HCoV-EMC/2012滴鼻感染288-330+/+小鼠模型

中文名称Chinese name	MERS-CoV HCoV-EMC/2012滴鼻感染288-330+/+小鼠模型
编号Model number
英文名称English name	MERS-CoV HCoV-EMC/2012 intranasally infection 288-330+/+ mouse model
物种Species name	小鼠
品系Strain name
人类疾病Human diseases	MERS
传染性Infectivity	是
微生物Microorganism
类别Category	MERS-CoV感染动物模型
造模因素Modeling factors
制作方法Making method	Viral titers for MERSCoV at 3 days p.i. from C57Bl/6J wild-type (n = 4), 288-330+/− (n = 4), and 288-330+/+ (n = 4) mice infected with the indicated viruses at 5×105PFU. PFU.
生物学特征Biological characteristics
医学用途Medical use	用于MERS致病机制研究、疫苗和药物评估。
临床表现Clinical manifestation
病理表现Pathology
发病天数Days of onset
发病过程Pathogenesis process
临床诊断Clinical diagnosis
评价模型成功的指标Indicators for evaluating model success
保藏单位Preservation unit	北卡罗来纳大学教堂山分校@@https://www.unc.edu/
参考文献Reference	A mouse model for MERS coronavirus-induced acute respiratory distress syndrome.,PMID:27892925,DOI:10.1038/nmicrobiol.2016.226
录入/更新时间Date	2021.7.20
备注Remarks