| 中文名称Chinese name
|
MERS-CoV hCoV-EMC 气管内感染猕猴模型 |
| 编号Model number |
|
| 英文名称English name |
MERS-CoV hCoV-EMC Rhesus Macaques intratracheally infected model |
| 物种Species name |
猴
|
| 品系Strain name |
|
| 人类疾病Human diseases |
MERS |
| 传染性Infectivity |
是 |
| 微生物Microorganism |
|
| 类别Category |
MERS-CoV感染动物模型 |
| 造模因素Modeling factors |
|
| 制作方法Making method |
Four monkeys, aged 2–3 years, were inoculated intratracheally with hCoV-EMC (6.5 × 107TCID50/1 mL) diluted in DMEM. |
| 生物学特征Biological characteristics |
|
| 医学用途Medical use |
用于MERS致病机制研究、疫苗和药物评估。 |
| 临床表现Clinical manifestation |
|
| 病理表现Pathology |
|
| 发病天数Days of onset |
|
| 发病过程Pathogenesis process |
|
| 临床诊断Clinical diagnosis |
病毒在肺中复制 |
| 评价模型成功的指标Indicators for evaluating model success |
|
| 保藏单位Preservation unit |
北京协和医学院@@http://english.cams.cn/index.html |
| 参考文献Reference |
An animal model of MERS produced by infection of rhesus macaques with MERS coronavirus.,PMID:24218506,DOI:10.1093/infdis/jit590 |
| 录入/更新时间Date |
2021.7.20 |
| 备注Remarks |
|
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